Best Mounjaro Alternatives (Updated) Top-Rated Natural OTC Tirzepatide Weight Loss Options

If you’ve heard about the infamous Tirzepatide drug, you must simply understand Mounjaro as its branded version.

Mounjaro is an injectable medicine that is primarily used to regulate and maintain healthy levels of blood sugar in people suffering from type 2 diabetes. It is also known for its weight-loss properties, making it a go-to medication these days.

Mounjaro is also FDA-approved for its incredible results in controlling blood sugar and managing type 2 diabetes. Apart from this, it is often prescribed off-label for weight loss purposes as well. This is because various studies have ascertained its effectiveness in boosting energy levels and promoting weight loss.

However, as ideal as it may seem, there’s much more to this drug than you can think of.

While Mounjaro is considered to be a potent medication, it comes with numerous risks and side effects both in the short-term and long-term. Moreover, it is quite a costly drug that is priced at $1,087 for a 2ml monthly supply.

We’ll dive into these aspects in detail, but first, let’s see how the drug works.

How Does Mounjaro Work?

There are two different hormones produced in our body after we consume sugar, namely glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These two are responsible for controlling the levels of blood sugar. Mounjaro acts as a receptor agonist of these hormones and works to imitate their actions.

By doing so, Mounjaro takes control of your appetite and helps you feel full with minimal eating. This leads to an increased feeling of satiety with lesser food consumption.

Mounjaro also results in a slower digestion process. This can help you implement portion control and regulate hunger levels. Apart from this, the drug also impacts some specific areas of your brain. It essentially targets the hypothalamus, the part of the brain that influences your appetite and eating patterns.

Through Mounjaro’s combined functioning on your digestion process, hormones, and the brain, it promotes effective weight loss. While results may vary across different individuals, it is recommended that you follow an extensive diet plan and consistent physical exercise to experience the best results.

What Are The Side Effects Of Mounjaro?

The list of risks and side effects associated with Mounjaro is immense. While some short-term effects end up diminishing in a few days or weeks, prolonged usage of the drug may also result in more severe and persistent side effects.

During clinical trials, the participants commonly experienced the following side effects:

  • Nausea
  • Diarrhea
  • Vomiting
  • Loss of appetite
  • Constipation

The drug is also likely to result in some more serious side effects, which are, while, uncommon but possible.

These include:

  • Pancreatitis
  • Hypoglycemia
  • Digestive issues
  • Allergic reactions
  • Gallbladder diseases
  • Severe diarrhea, vomiting, and nausea
  • Potential Thyroid Cancer

It is undoubtedly hard to ignore these dreadful side effects. This is why you need to steer clear of this potentially dangerous drug and choose a healthier alternative to lose weight.

While Mounjaro may certainly be effective, it is not worth taking the risk and exposing your body to such severe side effects.

What Are The Natural Alternatives To Mounjaro?

Mounjaro has proven its potency in various clinical trials. It is undeniably an effective drug, suited for maintaining adequate levels of blood sugar and promoting weight loss. However, this injectable drug is not an appropriate choice for most people. While it may have several benefits, it also comes with severe side effects.

This is why you must consider switching to a healthier and safer alternative that will also help you save a lot of money without compromising on the results.

Two of the best Mounjaro alternatives include:

  • PhenQ
  • Zotrim

Both of these supplements are available for purchase without needing any prescription. They’re made with natural and herbal elements that furnish almost similar results as Mounjaro. The best part is that both of these supplements are also backed by a money-back guarantee.

Let’s learn more about these natural alternatives.

Alternative #1: PhenQ: The Best Fat-Burning Alternative


PhenQ is a well-known supplement, featuring all-natural elements. It has and continues to help a large number of users opt for a sustainable way of weight loss.

What is PhenQ?

PhenQ is prepared with effective ingredients that provide a healthy boost of energy to the user and help them make the most of their regular exercise. It boosts metabolism which results in better physical activity and further promotes weight loss.

It stands as a much safer alternative to the harmful Mounjaro. Even if you use it for long periods, the natural components of PhenQ will only continue to benefit your body without causing any side effects.

How Does PhenQ Work?

PhenQ features a multi-faceted way of promoting weight loss and the general well-being of the user. The natural ingredients of PhenQ blend effectively to furnish the best results.

The supplement has energy-boosting and fat-burning properties that help improve thermogenesis and burn more calories in the body. PhenQ also works to suppress appetite and help you stay away from unhealthy cravings.

The supplement obstructs any new production of fat cells which further prevents accumulation of fat in your body. PhenQ constitutes various natural elements including amino acids that also offer various other health benefits.

How Is It Better Than Mounjaro?

Let’s see what makes PhenQ a better alternative to the infamous Mounjaro.

  • Non-Intrusive: Mounjaro, on one side, needs to be administered by a medical expert, making it quite an intrusive medication to use. Such a method of weight loss is not appreciated by a lot of people as they find it intimidating. However, PhenQ breaks this barrier as it can simply be consumed orally, making it a less intimidating, non-intrusive alternative.
  • Made with Natural Ingredients: Mounjaro is formulated with various sorts of chemicals that may lead to serious harm to your body. On the other hand, PhenQ is manufactured using all-natural elements, making it less prone to harmful side effects.
  • Effective for Weight Loss: Mounjaro is proven to accelerate weight loss as it makes use of some of the most potent chemicals. However, PhenQ also takes an almost comparable stand in promoting weight loss. Now the difference lies in sustainability and associated risks. As mentioned above, PhenQ is a much healthier way of losing weight that will have no side effects even with prolonged use.
  • Offers Money-Back Guarantee: The makers of PhenQ have also provided a generous money-back guarantee on the supplement which further proves its credibility. This shows the commitment of the creators and their belief in the product.
  • More Affordable: Mounjaro Tirzepatide can be quite an expensive way of losing weight. It needs the intervention of medical experts and can end up exceeding your budget. PhenQ, on the other hand, will cost you merely a fraction as compared to Mounjaro’s price. While Mounjaro is priced at more than a thousand dollars for a monthly supply, a 30-day supply of PhenQ is priced at only $69.99! This is a huge price difference that is hard to ignore.

Zotrim: The Herbal, Hunger-Reducing Alternative


If you’re looking for a natural and cheaper way of losing weight, Zotrim is the way to go. The potency of this natural supplement has been tested and verified by medical experts.

What Is Zotrim?

Zotrim is a natural supplement made with herbal ingredients and is available in the form of a pill. When undergoing clinical tests, this tiny pill surpassed various drugs that were previously considered to be ‘the best’. It is an affordable and safe alternative to harmful and costly drugs like Mounjaro.

To purchase Zotrim, you don’t need to submit any prescriptions or make doctor visits. It is a safe supplement that is readily accessible and easy to use.

How Does Zotrim Work?

Zotrim is an effective drug that works for both men and women. Reviews indicate that Zotrim has helped people shred considerable amounts of fat within just a month of use.

Every pill of Zotrim includes 6 powerful, natural, and fat-burning elements. These ingredients work to delay the process of gastric emptying in your body. In simpler words, it makes you feel full for a long time and curbs hunger.

Moreover, the natural ingredients present in Zotrim make it impossible to result in any side effects on your body. It is prepared with a powerful, plant-based trio of Damiana, Yerba Mate, and Guarana. These elements combine effectively to help you regulate your hunger levels and help you feel full for hours.

The truth is that Zotrim may not be as powerful as PhenQ, however, it’s still a much better and safer alternative to Mounjaro.

How Is It Better Than Mounjaro?

Let’s take a look at all the reasons that make Zotrim a better choice than Mounjaro:

  • Naturally Made: While Mounjaro is a prescription drug made with harmful ingredients that result in side effects, Zotrim is made with all-herbal and safe ingredients that are just as effective. The plant-based extracts present in this supplement work considerably to curb appetite, boost metabolism, and accelerate weight loss.
  • Clinically Tested: Zotrim has also undergone various clinical tests in which it surpassed three prominent weight loss drugs. While it may seem that Mounjaro is more effective due to its chemical composition, Zotrim showed comparable results with no side effects.
  • Sustainable Way of Losing Weight: The process of losing weight becomes much more sustainable and safe with the use of Zotrim. Its herbal ingredients help you control your hunger naturally without starving you or exposing your body to any kind of risk.
  • Doesn’t Require Prescription: Unlike Mounjaro, Zotrim is an over-the-counter supplement. This means that you can easily purchase it without needing to submit a prescription. This is in contrast with the intrusive Mounjaro that requires prescriptions, doctor visits, and medical administration.
  • More Affordable: Unlike the incredibly costly Mounjaro, Zotrim is much more reasonably priced. Zotrim is thus not only safe but also readily accessible.

Ingredients Used In Mounjaro Alternatives and The Science Behind Them

Below is a detailed overview of the most effective ingredients present in the Mounjaro alternatives listed above:

Nopal Cactus

Nopal cactus contains special compounds called pectin and mucilage. These substances help promote the absorption of dietary fat, Nopal cactus can contribute to weight loss and help maintain healthy cholesterol levels.

A study conducted on Nopal cactus further supports its efficacy in promoting healthy weight loss and suppressing appetite. The study investigated the effects of Nopal cactus supplementation on overweight and obese individuals. The group taking Nopal cactus extract witnessed an average weight loss of 4.5 pounds compared to only 1.5 pounds in the placebo group.


Guarana is a natural ingredient that is often added to Mounjaro alternatives to enhance fat-burning results and promote metabolic function.

One mechanism by which Guarana may improve fat-burning results is through its stimulatory effect on the central nervous system. Guarana contains a high concentration of caffeine, a well-known stimulant. This can lead to increased energy expenditure and thermogenesis, both of which can contribute to fat burning.

Furthermore, Guarana has been shown to enhance lipolysis, the breakdown of stored fats into free fatty acids. This is due to its ability to stimulate the release of epinephrine, a hormone that triggers the breakdown of fat cells.

Epinephrine activates hormone-sensitive lipase, an enzyme that breaks down triglycerides into glycerol and free fatty acids. These free fatty acids can then be used as a source of energy during physical activity, further promoting fat burning.

Alpha Lacys Reset

Alpha Lacys Reset combines two powerful ingredients, alpha-lipoic acid and cysteine. These ingredients work in harmony to achieve optimal results. Alpha-lipoic acid is an antioxidant that helps to convert glucose into energy, preventing it from being stored as fat.

It also enhances insulin sensitivity, which aids in the regulation of blood sugar levels. Cysteine, on the other hand, is an amino acid that supports the production of glutathione, a potent antioxidant that helps to eliminate harmful toxins from the body.

The synergistic combination of alpha-lipoic acid and cysteine in Alpha Lacys Reset results in various benefits for weight optimization.


Furthermore, caffeine can also increase the metabolic rate, which refers to the number of calories burned at rest. This effect is known as thermogenesis, and it occurs due to caffeine’s ability to stimulate the central nervous system.

As a result, the release of neurotransmitters like dopamine and norepinephrine is increased, leading to an overall increase in metabolic rate.

In addition to its impact on lipolysis and thermogenesis, caffeine can also enhance endurance performance during exercise. By stimulating the central nervous system, caffeine can reduce the perception of effort and fatigue, allowing individuals to exercise for longer durations.

Yerba Mate

This herbal drink, derived from the leaves of the Yerba Mate plant, contains a unique combination of compounds that work synergistically to provide a natural and sustained energy boost while supporting weight loss efforts.

One of the key components of Yerba Mate is caffeine. However, unlike the caffeine found in coffee or tea, Yerba Mate contains a balanced blend of caffeine, theobromine, and theophylline.

This combination results in a more gradual and sustained release of energy, preventing the sudden spikes and crashes associated with other caffeinated beverages. Additionally, the presence of theobromine and theophylline in Yerba Mate contributes to its thermogenic properties, which can aid in weight loss.

Furthermore, Yerba Mate contains a group of compounds known as saponins. These saponins have been found to have anti-obesity effects by reducing the absorption of dietary fat and cholesterol.


Damiana helps promote appetite suppression by increasing feelings of satiety. Research suggests that consuming Damiana extract can stimulate the release of certain hormones in the body, such as cholecystokinin (CCK) and glucagon-like peptide-1 (GLP-1), which are responsible for signaling fullness and reducing food intake, promoting calorie deficit.

A study conducted to assess Damiana’s effects on appetite suppression and calorie deficit involved a randomized, double-blind, placebo-controlled trial. The study involved 90 overweight participants who were divided into three groups: a placebo group, a low-dose Damiana group, and a high-dose Damiana group.

The statistics from the study revealed that the low-dose Damiana group reported a 15% decrease in overall appetite, while the high-dose group experienced an impressive 25% decrease.

Our Final Thoughts

In the realm of calmness, Mounjaro reigns supreme with a tranquil grip that makes stress go “Poof, be gone!” Its natural alternatives? Well, they’re like Mounjaro’s equally zen cousins at a family reunion.

If you’re into a more herbaceous journey, Mounjaro’s natural alternatives are like a scenic route through the valleys of calm and boosted fat burning. So, whether you’re team Original or team Nature, Mounjaro has concocted potions that say, “Chill vibes only, please!”

So why not give excess weight to the old heave-ho with a touch of Mounjaro magic?