Reviewing the Best Nootropic Supplements and Brain Booster Pills

Are you looking for a way to boost your memory, enhance your cognitive function, and improve overall mental health? If so, natural nootropics may be the solution for you, as many people have found that these natural supplements have helped them do just that!

Some types of nootropic supplements support and increase blood flow to the brain. In contrast, others utilize blends of plants, vitamins, herbal extracts, and minerals that work together and provide mutually beneficial benefits for brain health. People of all ages, from elderly adults to professionals who work in demanding environments, athletes to university students, and anyone looking for a way to support brain health and enhance their cognitive function, found nootropic supplements help them achieve their goals.

If you’re interested in giving nootropic supplements a try for yourself, you’re going to find that there are so many different options available. While choice is always a good thing, with such a large array of supplements to choose from, trying to narrow down the options and decide which one to use can be a challenging task. To help you on your quest for finding the best nootropic, we’ve taken the liberty of researching for you. After spending countless hours researching dozens of nootropic supplements, we’ve narrowed down the options to what we believe are the best of the best. Below, we’ve compiled a list of our top picks for the best nootropic supplements currently available on the market. So, if you’re ready to increase your cognitive function, keep on reading!

The Top 33 Best Nootropic Supplements for Brain Health

All-natural nootropics tout their ability to support and increase brain health and cognitive function. Of course, as with every other product, some of those claims aren’t founded and are just that – claims. The truth is that some the nootropic supplements do offer the benefits they claim, while others simply don’t. We’ve weeded through dozens of different nootropics and found the supplements that live up to their claims.

Here’s a list of the best nootropic supplements that have been scientifically proven to support brain health and boost memory and cognitive function.

Vitaae By Saane Labs Help people to improve brain utilization
Mind Lab Pro Improves alertness and concentration
Nuzena Neuro Focus Plus Enhances feelings of relaxation and fortifies memory
NooBru Helps in fighting stress to improve mood
Nootrogen It helps in improving mental functioning and reserving energy
Ageless Brain Protects the brain from age-related damage
Onnit Alpha Brain Enhances development of brain cells and improves memory
Hunter Focus Enhances learning ability and memory functions
Qualia Mind Decreases procrastination and produces more energy
Performance Lab Mind Encourages blood flow for better brain functioning
Vital Plain Brain Boost Fights with brain fogging and enhances focus
Natural Cell Neuro Activ6 Improves clarity of thinking and alertness
Synapse XT Reduces brain fatigue and provides tinnitus relief
NooCube Enhances concentration and focus
Natural Stacks Neuro Fuel Allows faster rate of memory processing
Upwellness Mind and Mood Provides calmness and relaxation to the mind
Pure Essense Brain Essence Boost healthy stress response
Ageless Brain by Pure Health Elevate memory, focus, and alertness
Brain C-13 Promotes overall health and wellness
Cymbiotika Golden Mind Protects the brain from oxidative stress
Elm and Rye Nootropics Supports increased productivity and stamina
Cognibiotics Improves mental clarity and learning memory
NeuroLive by Amy Myers Supports overall brain tissue health
Neuro Decreases stress and anxiety
OptiMind Boost better social skills and mood
Youthful Brain Combat brain aging and boost mental abilities
Oweli Neuro Reduces stress and boost energy
Remind Solution Boost your mental and cognitive power
Brain Pill Improve brain function and boost memory
ProMind Complex Increases neurotransmitters in the brain
Memory Hack Regains memory power and improves mental health
Memo Surge Reduces memory loss problem
Memo Defend Boost faster recovery from memory loss

Let’s dive in and take a look at each of these supplements so that you can decide which one will best suit your unique needs. Below, we break down each supplement, including the ingredients, the benefits they provide, and their efficacy.

SANE Laboratories Vitaae


SANE Laboratories Vitaae is one of the best nootropic supplements on the market. Whereas many nootropic supplements use vitamins and herbal extracts, Vitaae uses a blend of antioxidants, such as CoQ10, which has been proven to target brain inflammation. SANE Laboratories reports that their supplement could boost brain power by as much as 13.6 percent and increase membrane turnover by up to 26 percent. Those are just some of the unique benefits that their formula provides.

Ingredients Folate, Vitamin D, L-carnitine, Acetyl, Omega-3 fatty acids, CoQ10 and Citicoline
Key Highlights
  • Promote healthy brain function
  • Offers various cognitive abilities
  • Reduces brain fog and mental fatigue
  • Boost mental performance
  • Price $47
    Money-Back Guarantee 365 days

    Mind Lab Pro


    One of the best nootropic supplements on the internet, Mind Lab Pro, is specially formulated with various ingredients that have been proven to support brain performance, enhance memory, and improve multiple cognitive functions. While it’s one of the pricier options, it offers a wealth of benefits and is an excellent introduction to those who are just getting started with nootropics.

    Made by Opti-Nutra, one of the most trusted supplement manufacturers on the market that even has a medical advisory board led by Dr. Ramon Velazquez, Ph.D. neuroscientist, it’s easy to see why Mind Lab Pro is so well-respected and popular.

    Ingredients Lion’s mane mushroom, Bacopa monnieri, Citicoline, Phosphatidylserine, and Rhodiola Rosea extract
    Key Highlights
  • Supports healthy brain cells
  • Enhance brain energy
  • Boost cognitive performance
  • Optimize brain health
  • Price $69
    Money-Back Guarantee 30 days

    Nuzena Neuro Focus Plus


    This nutritional supplement is specially formulated as a cognitive enhancer that supports memory, boosts mental clarity, and various other brain functions. Made in the USA, Neuro Focus + is another one of the top-rated nootropics supplements. Each serving of this nootropic supplement is packed with a proprietary blend of vitamins and minerals that have been proven to support brain function.

    The natural nootropic ingredients that Neuro Focus + contains are one of the reasons why it is such an appealing supplement.

    Ingredients Glutamic acid, DMAE bitartrate, Green tea extract, and Bilberry fruit extract
    Key Highlights
  • Repairs damaged brain cells
  • Improve focus and mental acuity
  • Offers long term brain health
  • Prevent slow cognitive decline
  • Price $30
    Money-Back Guarantee 90 days



    NooBru came onto the scene in 2020, making it one of the newest nootropic supplements on the market. Thanks to a proprietary blend of 13 active ingredients and a taste bud-pleasing flavor (and a lot of focus from the media), NooBru has quickly become one of the most popular nootropics supplements available. It’s primarily marketed to older adults, athletes, students, and those who work in competitive industries that demand a great deal of mental clarity and focus.

    NooBru is different from other supplements on our list, as it’s offered in powder form instead of capsules, which you can dissolve and drink in water or juice. Each dose contains a powerful blend of ingredients that have been proven to support brain function.

    Ingredients Vitamin B53, Alpha GPC, L-theanine, Choline bitartrate, Ashwagandha, and Huperzine A
    Key Highlights
  • Promotes brain cell development
  • Boost mental function
  • Enhances cognitive functions
  • Increases brain energy utilization
  • Price $55
    Money-Back Guarantee 90 days



    Another nootropic supplement designed to improve cognitive function, boost energy, enhance focus, and reduce stress, Nootrogen users swear by this formula. While the manufacturer’s promises are the same as the other nootropic supplement makers on our list, this option is made with unique ingredients that aren’t used in others.

    Every two capsules serving size offers a 642 mg dose of proprietary ingredients, including amino acids, herbal extracts, and plant extracts that have been proven to support and improve cognitive function in many ways.

    Ingredients DMAE, amino acids, Glutamic acid, and L-tyrosine
    Key Highlights
  • Boost brain cell growth
  • Enhance cardiovascular health and overall wellness
  • Enhances mental processing speed
  • Provides mental clarity and focus
  • Price $30
    Money-Back Guarantee 180 days

    Organixx Ageless Brain


    Organixx Ageless Brain is a nutritional supplement that is jam-packed with many of the ingredients that other formulas on our list contain, such as Bacopa monnieri, and unique elements that aren’t used in others make it a genuinely unique nootropic.

    While more research is needed to verify the effects of Ageless Brain, the manufacturer claims that their formula supports cognitive health in various ways.

    Ingredients Camu Camu, Cat’s claw, Dragon’s blood, Cinnamon Cacao
    Key Highlights
  • Reduces nervousness and anxiety
  • Boost brain function
  • Increases mental energy and performance
  • Enhance problem-solving skills and learning ability
  • Price $55
    Money-Back Guarantee 365 days

    Onnit Alpha Brain


    Said to be the best nootropic supplement on the market and, indeed, one of the most popular, Onnit Alpha Brain, claims to provide many mental benefits. Joe Rogan, the popular podcaster, is the co-owner of Onnit. He regularly promotes the supplement, stating that it boosts brain function, improves memory power, and increases focus and cognition.

    Alpha Brain is one of the few dietary supplements on our list backed by clinical trials and peer-reviewed research. Most supplement makers don’t bother investing in either due to the high cost, which certainly speaks volumes about Onnit and its commitment to providing a premium product. When you take Onnit’s Alpha Brain, you can have confidence knowing that you’ll be taking a top-quality supplement that is scientifically proven to be healthy and effective.

    Ingredients Cat’s claw, Oat stage, Bacopa monnieri and Huperzia Serrata
    Key Highlights
  • Provides various cognitive benefits
  • Repairs and nourish healthy brain cells
  • Increases brain energy
  • Boost mental performance
  • Price $35
    Money-Back Guarantee 90 days

    Roar Ambition Hunter Focus


    Roar Ambition Hunter Focus is a nootropic formula that offers an edge over others. This supplement improves focus and mental clarity through a premium-quality formula of all-natural nootropic ingredients.

    The ingredients have been found to reduce mental fatigue and stress and increase mental clarity, cognitive function, and memory power. With a recommended serving size of 4 capsules, Hunter Focus is one of the highest dosages on our list of nootropic supplements, hence why it’s one of the most popular options on the market.

    Ingredients Passion flower, Bacopa monnieri and Phosphatidylserine
    Key Highlights
  • Boost brain cell development
  • Enhances various cognitive benefits
  • Improves nerve growth factor
  • Boost mental performance
  • Price $60
    Money-Back Guarantee 90 days

    Qualia Mind


    Made by Neurohacker Collective, Qualia Mind is another one of the super-popular nootropic supplements out there. It’s made with an assortment of active ingredients that have been proven to offer powerful effects. The formula contains 28 active ingredients that support mental focus, memory, brain function and even improve energy levels.

    Another critical benefit of Qualia Mind is the customization options that are offered, which includes four different formulas:

    • Qualia Mind
    • Qualia Mind Caffeine Free
    • Qualia Mind Essentials
    • Qualia Focus
    Ingredients Huperzia Serrata Leaf extract, Celastrus Paniculatus seed extract, Theobromine, Bacopa Monnieri leaf extract, Ginkgo biloba leaf extract, Velvet bean, Organic Coffeeberry
    Key Highlights
  • Stimulates the brain and central nervous system
  • Improve focus and memory power
  • Boost mental processing speed and mood
  • Enhance cognitive abilities and memory retention
  • Price $59
    Money-Back Guarantee 100 days

    Performance Lab Mind


    Performance Lab Mind has appropriately named their nootropic formula “Mind.” According to the manufacturer, this Performance Lab Mind boosts brain energy levels by nearly 14 percent, supports focus and memory, increases motivation, and enhances recovery from intensive cognitive tasks.

    Performance Lab Mind is made with various vital ingredients proven to support brain health. Natural ingredients nourish your body with a powerful blend of essential vitamins, minerals, antioxidants, and other essential elements that are proven to help cognitive health in various ways.

    Ingredients Phosphatidylserine, Citicoline, L-tyrosine, Maritime pine bark extract, Rhodiola Rosea, and Ginkgo Biloba
    Key Highlights
  • Enhance long term brain health
  • It opens all brain pathways for better brain function
  • Improves mental performance and health
  • Increases blood flow to optimize brain health
  • Price $69
    Money-Back Guarantee 30 days

    Vital Plan Brain Boost


    Vital Plan Brain Boost is a nootropic supplement developed by Dr. Bill Rawls, MD. Dr. Rawls claims that his brain supplement boosts memory recall, increases cognitive function, enhances mental clarity, improves focus, supports immunity, boosts energy levels and mood while reducing stress levels, and even benefits the gut’s microbiome. Those are just some of the benefits that are touted.

    The labeling on this formula is very transparent, the dosages are potent, and it’s free of proprietary blends, hence why it’s one of the most trusted and effective nootropics in 2021. With a serving size of four capsules, Brain Boost is one of the most potent nootropic supplements on the market. Brain Boost is an excellent choice if you’re looking for a highly effective yet affordably priced option.

    Ingredients Ginkgo Biloba, Bacopa monnieri, Ashwagandha, Lion’s mane mushroom, and Cat’s claw extract
    Key Highlights
  • Reduces cognitive decline
  • Alleviate mental fatigue and provide mental benefits
  • Produces more brain chemicals
  • Increases mental acuity and cognitive performance
  • Price $48
    Money-Back Guarantee 90 days



    Made by NaturalCell, NeuroActiv6 is a powdered nootropic supplement. The super-fine powder is designed to support brain function, boost focus, and increase clarity, just to name a few of the benefits.

    To take NeuroActive 6, simply mix a scoop of the powder into a beverage of your choice once per day, and according to the manufacturer and users, you’ll start to experience a noticeable difference in your energy levels and your mental clarity and focus. It’s also said to increase BDNF levels, improve cortisol levels, and promote neural communication. It’s made with a blend of nootropic superfoods, such as:

    If you’re on the market for an easy way to improve your brain function, NeurActive6 is an excellent choice. Mix it into your daily smoothie, a glass of water, juice, or any other beverage, and you should see a marked increase in your mental function.

    Ingredients Ashwagandha, Turmeric, Grape seed extract, B vitamins, Coffee fruit extract, and Citicoline
    Key Highlights
  • Boost mental energy and cognitive abilities
  • Improves brain function and mental energy
  • Enhance cognitive performance
  • Increases blood flow to the brain
  • Price $46
    Money-Back Guarantee 60 days

    Synapse XT


    Made with a blend of essential vitamins and minerals derived from plants and herbs, Synapse XT claims to boost brain health and improve hearing. This nootropic supplement may be the perfect option for older adults concerned about cognitive decline and experiencing hearing difficulties.

    By taking the recommended serving size of two capsules per day, you can support and enhance your memory, focus, and hearing function. The ingredients used in this formula work together to communicate between cells that play a vital role in all of these essential functions, thereby reducing the effects of brain fatigue.

    The makers of Synapse XT tout that their formula supports the perception of the senses and sounds while transforming and improving your overall health and life by promoting clearer thinking and hearing. While it’s one of the more expensive options on our list, given the fact that it supports both brain and hearing health, it’s a worthwhile investment.

    Ingredients Hibiscus extract, Garlic, Hawthorn berry, amino acid, and Vitamins
    Key Highlights
  • Enhances hearing ability
  • Promotes cognitive functions
  • Responsible brain cell regeneration
  • Improves mental processing speed
  • Price $69
    Money-Back Guarantee 60 days

    NooCube Brain Productivity


    Leading neuroscientists developed this brain supplement after many clinical trials. NooCube Brain Productivity is different from other nootropic supplements on the market, as it is entirely free of caffeine. Instead, it’s made with a unique blend of natural plant and herbal extracts and other key active ingredients that have been proven to provide various cognitive benefits.

    Ingredients Huperzine A, Alpha GPC, Cat’s claw extract, ginkgo Biloba, lion’s mane mushroom, n-acetyl l, and Bacopa monnieri
    Key Highlights
  • Enhance memory retention and promote the development of new brain cells
  • Responsible for better mental performance
  • Prevent slow cognitive decline
  • Boost brain function and mental energy
  • Price $60
    Money-Back Guarantee 60 days

    Natural Stacks NeurolFuel


    Natural Stacks’ makers of NeuroFuel claim that their nootropic supplement targets various mental health issues, such as brain fog, cognitive decline, and memory impairment. While the ingredients used in this formula are similar to those in other brain supplements, NeuroFuel offers a distinct and unique advantage. For example, all of the ingredients used are traced and sourced on the blockchain, making it the only “open source” nootropic on our list.

    NeuroFuel is made with an assortment of premium-quality, all-natural ingredients that support brain function and mental performance. Plus, since it uses substantial amounts of a small number of elements instead of small quantities of a large variety of ingredients, NeuroalFuel may yield more effective results than other formulas on our list.

    Ingredients Forskolin, Artichoke extract, Vitamin B6, and amino acids Acetyl L-carnitine
    Key Highlights
  • Enhance mental function and brainpower
  • Produces more brain chemicals
  • Supports nerve growth factor
  • Enhance memory retention
  • Price $30
    Money-Back Guarantee 30 days

    Mind & Mood


    Made by UpWellness, this brain supplement improves cognitive health, boosts memory, and increases mental focus. It also helps to reduce anxiety and stress levels while improving emotional well-being.

    According to the manufacturer and users, by taking Mind & Mood daily, your nervous system will relax, and you’ll feel markedly calmer. It’s made with natural ingredients that offer potent benefits—formulated by Dr’s Joshua and Amanda Levitt, Mind & Mood is one of a handful of nootropic supplements on our list made by real doctors and goes through many clinical trials.

    Ingredients 5-HTP, Lion’s mane mushroom, Rhodiola Rosea, amino acids, L-theanine, saffron, and GABA
    Key Highlights
  • Enhance memory retention and clarity
  • Reduces stress and anxiety
  • Increases the blood flow to the central nervous system
  • Boost cognitive function
  • Price $57
    Money-Back Guarantee 60 days



    BrainEssence, a nootropic supplement by Pure Essence, is specially formulated to support memory, focus, clarity, energy levels, and even enhance mood. Made in tablet form, as opposed to capsules or powder, like most of the other supplements on our list, the manufacturer recommends taking two tablets daily to take full advantage of the cognitive health benefits the formula purports.

    All of the ingredients and dosages are fully disclosed by PureEssence, which makes it easy to see what you’re ingesting. The formula is made up of a collection of high-quality ingredients.

    Ingredients Bacopa monnieri extract, Acetyl l-carnitine, Ashwagandha, Rhodiola Rosea, extract, Alpha-lipoic acid, and Chinese club moss extract
    Key Highlights
  • Produces new brain cells
  • Boost mental performance and brain chemicals
  • Enhance brain power and performance
  • Support mental acuity and clarity
  • Price $30
    Money-Back Guarantee 90 days

    PureHealth Research Ageless Brain


    This is the second Ageless Brain nootropic supplement on our list. This brain supplement was formulated by Dr. Holly Lucille, an acclaimed doctor who is fully committed to improving her patients’ mental health and cognitive function.

    This supplement is made with a collection of ingredients that have been carefully selected for the benefits they provide.

    The recommended dosage is one capsule a day, which is purported to reduce brain fog and anxiety levels, boost memory and focus, and increase memory and cognitive wellness. Those are just a few of the benefits. Despite the advantages, there is a downside to Ageless Brain. It uses a proprietary formula of 600mg of active ingredients; however, the manufacturer does not disclose a breakdown of each of the elements used, so you can’t determine how much of which ingredients you’re getting with each dose. With that said, however, if you aren’t concerned about the disclosure of this information, Ageless Brain is said to be a premium-quality supplement that yields highly effective results, and it may be the right choice for you.

    Ingredients B vitamins, GABA, amino acid, Lion’s mane mushroom, caffeine, and Huperzine A
    Key Highlights
  • Enhance memory retention and focus
  • Boost mental performance and function
  • Enhances concentration and learning abilities
  • It opens all brain pathways for better brain function
  • Price $44
    Money-Back Guarantee 365 days

    Zenith Labs Brain C-13


    Made by Zenith Labs, one of the most trusted manufacturers of a variety of dietary supplements, Brain C-13 is comprised of a collection of premium-quality vitamins and minerals, as well as herbal and plant extracts. Some of the ingredients that Brain C-13 contains include:

    Zenith Labs fully discloses the ingredients they use and the amount of those ingredients used in each dosage, so it’s easy to compare this supplement to other top-quality nootropic supplements on our list. With a recommended dosage of three capsules per day, the dosing of Brain C-13 is more substantial than other supplements, which suggest two or one capsules a day. Like other supplements made by Zenith Labs, Brain C-13 is formulated by doctors and is fully supported by a medical advisory board.

    Ingredients Rhodiola root extract, DMAE, Rosemary leaf, Ginkgo biloba leaf, Turmeric, Phosphatidylserine, Huperzine A, and amino acid
    Key Highlights
  • Enhances problem-solving and learning abilities
  • Reduces age-related cognitive decline
  • Boost memory retention, focus, and clarity
  • Increases brain cell growth
  • Price $49
    Money-Back Guarantee 180 days

    Cymbiotika Golden Mind


    Cymbiotika Golden Mind is the only nootropic supplement on our list in a liquid tincture form instead of a capsule or powder. Every serving of Golden Mind consists of a variety of active ingredients that are proven to support brain health and improve cognitive function.

    A blend of 82 ocean minerals and an assortment of other unique ingredients are in every serving. By taking Golden Mind daily, the manufacturer purports that you will notice a reduction of brain fog, you’ll see an improvement in your focus and memory recall, and you’ll notice a marked improvement in your overall mood.

    Ingredients Lion’s mane mushroom, Phosphatidylcholine, L-theanine, Rhodiola Rosea, Sea buckthorn oil, Gotu kola extract, and essential amino acid
    Key Highlights
  • Work as great cognitive enhancers
  • Responsible for better mental performance
  • Ensures enhanced brain function by producing more brain cells
  • Boost problem-solving abilities
  • Price $50
    Money-Back Guarantee 30 days

    Elm & Rye Nootropics


    Elm & Rye is the most expensive nootropic supplement on our list. This brain supplement is made of various ingredients proven to target and boost focus and memory, increase attention span, and boost productivity and stamina. Those are just some of the benefits that it is said to provide. Given those advantages, the high price may be worth the investment.

    Each dose also offers up an impressive 268mg of caffeine, which will help to improve your energy level; however, equivalent to two to three cups of coffee, if you’re concerned about your caffeine intake, this may be a concern for you.

    Ingredients Alpha GPC, Bacopa monnieri extract, L-theanine, ginkgo Biloba, L-tyrosine, B vitamins, and Phosphatidylserine extract
    Key Highlights
  • Improve brain function and memory power
  • Naturally produces more brain cells
  • Supports cognitive functioning
  • Reduces stress and anxiety
  • Price $85
    Money-Back Guarantee 100 days



    This nootropic supplement is made with a blend of ingredients that claim to improve brain function, boost mental clarity, enhance learning, support memory power, and strengthen focus. While it claims to offer many of the same benefits that other nootropics on our list offer, CogniBiotics helps improve digestion, too, which is essential, as gut health directly impacts cognitive health.

    The gut’s microbiome comprises a variety of healthful bacteria that have a profound impact on brain function, and thus, have directly affected brain performance. CogniBiotics is made with a blend of 17 nootropic and adaptogenic herbs that improve cognitive health, boost mood and reduce stress levels by enhancing gut flora. It also offers ten probiotic strains of bacteria known to support the brain. If you’re looking to support the health of your brain uniquely, then CogniBiotics is a nootropic supplement that is certainly worth considering.

    Ingredients Cristaria plicata shell, Eclipta prostrate, Citrus reticulata, Paeonia Lactiflora, Schisandra Chinensis, Cristaria plicata shell, Prebiotic complex
    Key Highlights
  • Regenerates damaged brain cells
  • Enhances mental energy and performance
  • Deals with everyday stress levels and nervousness
  • Boost focus, concentration, and memory
  • Price $62
    Money-Back Guarantee 365 days

    Amy Myers MD NeuroLive


    Formulated by Amy Myers, MD, NeuroLive is specially made to boost brain function and performance and functions as a premium cognitive enhancer. The nootropic supplement used in NeuroLive is made with seven high-profile micronutrients that support brain performance.

    All ingredients added to this nootropic supplement have been carefully selected. They work together to offer a powerful and highly effective attack against free radicals, thus helping to combat the impact of oxidative damage. It’s also made with phosphatidylserine, which is patented to support brain cell membrane health. This nootropic formula by Amy Myers, MD, supports healthy memory and recall via a one-of-a-kind blend of active nutrients that promote energy production within the brain.

    Offering a long list of health benefits, which you can view on the supplements page of the Amy Myers MD website, this nootropics supplement supports healthy vasculature. It promotes optimal blood flow better than almost every other product currently available. With free shipping and backed by third-party lab testing, you will have complete confidence knowing that you’ll be purchasing a premium-quality nootropic when you opt for NeuroLive.

    Ingredients Vitamin B6, Mucuna pruriens seed extract, Bacopa monnieri whole plant extract, Ginkgo biloba leaf extract, Sharp-PS GREEN Phosphatidylserine, N-Acetyl Tyrosine/L-Theanine, and essential amino acid
    Key Highlights
  • Boost cognitive and mental health
  • Reduces stress and depression symptoms
  • Enhances learning and problem-solving abilities
  • Increases brain energy and mental performance
  • Price $49.97
    Money-Back Guarantee 90 days



    Next on our list of the best nootropic supplements is unique, Neuro, as it’s the only option offered in gum and mint form. With Neuro, you’ll not only boost your focus, improve your concentration, increase your energy, and feel calmer, but you’ll also freshen your breath.

    These gums and mints are offered in three different varieties, including:

    • Energy and Focus
    • Calm and Clarity
    • Ideal State

    They’re available in two fresh flavors, too: peppermint and cinnamon. If you’re interested in boosting your well-being and improving your focus while also enhancing your breath, Neuro may be the right nootropic for you.

    Ingredients Sorbitol, Gum Base, L-theanine, Natural Flavors, Natural Caffeine, Calcium Stearate, Spirulina Flakes, Sucralose, Monk Fruit, Stevia, Pyridoxine
    Key Highlights
  • Soothes and relaxes nerve cells for better performance
  • Improve brain health
  • Enhances cognitive functions
  • Increases mental performance and blood flow for better brain working
  • Price $21
    Money-Back Guarantee 30 days



    A nootropic supplement specially formulated to improve mental energy, enhance focus, and support cognition, thanks to a unique blend of proven ingredients. The key active ingredient used in this formula is Bacopa monnieri, which contains 55 percent bacosides, the active compounds found in the Bacopa monnieri plant, which gives this supplement the benefits it purports.

    By taking OptiMind daily, you’ll notice a marked increase in your cognitive health and your mood.

    Ingredients Phosphatidylserine, bacopa monnieri, Rhodiola Rosea, maritime pine bark extract, taurine, vinpocetine, GABA, and caffeine
    Key Highlights
  • Decreases mental fatigue and stress levels
  • Boost self-confidence, concentration, and focus
  • Enhances various cognitive abilities
  • Reduces brain fogging
  • Price $30
    Money-Back Guarantee 30 days

    Vitality Now Youthful Brain


    Youthful Brain by Vitality Now is a nootropic supplement designed to support mental energy, improve cognitive power, and boost overall brain health, thanks to a combination of active ingredients.

    While the ingredients used in this formula are similar to the elements used in several other nootropic supplements on our list, they are at lower doses, which puts Youthful Brain lower on our list; however, it’s still a viable supplement for brain health.

    Ingredients Bacopa monnieri, phosphatidylserine, rhodiola rosea, Ginkgo Biloba, and huperzine A
    Key Highlights
  • Boost mental and physical performance
  • Improves mental energy
  • Reduces brain fogging and mental fatigue
  • Naturally helps in the production of brain chemicals
  • Price $65
    Money-Back Guarantee 60 days

    Oweli Neuro


    Oweli Neuro, also simply known as “Neuro,” is a one-of-a-kind nootropic that encourages focus that has been said to be “zen-like.” The recommended daily serving size is two capsules, enhancing memory, boosting learning, supporting neuroplasticity, and even helping fight age-induced cognitive decline. Those are just some of the benefits it provides.

    With every two capsules serving size of Neuro, you’ll get a healthy dose of ingredients that have been proven to improve concentration, enhance cognitive function, boost memory, improve mood, reduce stress, and increase productivity.

    Ingredients Bacopa monnieri, Huperzine A, B vitamins, Phosphatidylserine, Inositol and DMAE
    Key Highlights
  • Improves concentration, focus, and self-confidence
  • Reduces the symptoms of memory loss
  • Alleviate stress and anxiety-related symptoms
  • Boost brain productivity
  • Price $30
    Money-Back Guarantee 100 days

    ReMind Solution


    ReMind Solution is a nootropic supplement that contains a collection of ingredients that have been clinically proven to combat anxiety and stress, minimize cognitive issues, boost focus levels, and support overall brain function. The benefits are very similar to other options on our list, yet they are sold higher.

    Ingredients St. John’s Wort, L-Glutamine, Phosphatidylserine, Bacopa Monnieri, Ginkgo Biloba, N-acetyl L-carnitine (NALC or NAC), vinpocetine, and Huperzine A
    Key Highlights
  • Combat stress and anxiety-related symptoms
  • Minimizes cognitive problems
  • Boost concentration and focus levels
  • Improves memory and brainpower
  • Price $69
    Money-Back Guarantee 60 days



    BrainPill claims an “unfair advantage” over other nootropic supplements. The manufacturer touts that it can eliminate brain fog, combat mental fatigue, protect and enhance memory, spark rapid recall, promote cognitive energy, and boost learning capabilities. Those are just some of the benefits that it claims to provide.

    With each serving of BrainPill, you’ll receive 13 nootropics that are proven to be beneficial for brain function and promote all-day focus without causing a crash. Recommended by Dr. Dave David, BrainPill says that it can improve cognition without unwanted side effects, such as jitters. Furthermore, unlike many of the other dietary supplements on our list, BrainPill is caffeine-free; instead, it uses natural ingredients that are proven to boost brain function without causing a crash.

    While BrainPill does tout a long list of benefits, there is one downside: a high price tag. It’s more expensive than many of the supplements on our list. It’s also hard to determine the specific dosages of many of the ingredients that BrainPill contains. The manufacturer claims that it uses “hefty” and “proper doses” of active ingredients, but they don’t disclose those ingredients, which puts it lower on our list of other brain supplements on our list.

    Ingredients B vitamins, n-acetyl-l-tyrosine, zinc, DMAE, bacopa monnieri, Huperzine A, phosphatidylserine
    Key Highlights
  • Defeat aging mental issues
  • Boost mental processing speed and brainpower
  • Improves brain energy and brain performance
  • Increases blood flow to the central nervous system
  • Price $69.95
    Money-Back Guarantee 60 days

    ProMind Complex


    Created by Carl Henderson, a man who claims that he has decades of experience formulating and developing the ideal nootropic supplement, ProMind Complex does support brain health; however, it falls short regarding active ingredients and dosages.

    The natural ingredients added in this nootropic stack are prevalent, as they have been proven to offer nootropic effects. With that said, however, the dosages of these ingredients are questionably low, especially considering the high price of these supplements. Furthermore, this supplement only comes with 30 capsules per bottle. ProMind Complex is the smallest option on our list. Users do say, however, that it does offer noticeable benefits.

    Ingredients Phosphatidylserine, L-glutamine, Bacopa monnieri extract, Huperzine A and Vinpocetine
    Key Highlights
  • Restores damaged brain cells and nerves
  • Improves brain functioning with better brain power
  • Reduces stress and depression symptoms
  • Boost self-confidence and focus
  • Price $69
    Money-Back Guarantee 60 days

    Nutrition Hacks Memory Hack


    Nutrition Hacks Memory Hack is one of the more expensive nootropic supplements on our list; furthermore, it doesn’t list the ingredients or dosages. Additionally, the manufacturer claims that their supplement can deliver “total restoration of memory in six months,” which is something that very few makers of nootropic supplements claim, offering those who are suffering from memory disorders unrealistic expectations. With that said, however, Memory Hack is backed by a 60-day money-back guarantee, and all purchases come complete with a bonus guide, which allows you to maximize the value. As long as you’re aware of the downsides, these benefits may make trying Memory Hack worth your while.

    Ingredients L-theanine Vitamin B3, Vitamin B6, and Vitamin B12 Ginkgo Biloba ​Phosphatidylserine
    Key Highlights
  • Treats short term memory loss problem
  • Reduces the chances of memory loss
  • Boost focus and clarity
  • Provides sharper memory and enhances self-confidence
  • Price $69
    Money-Back Guarantee 60 days



    MemoSurge claims that it works in a three-step process, which includes:

    • Firing up neurotransmitters in the brain
    • Repairing damaged brain cells and eliminating brain shrinkage
    • Eliminating anxiety and insomnia, thus increasing energy level

    Furthermore, MemoSurge also touts that it can optimize your overall health and well-being. This nootropic supplement offers little information about the ingredients included in the formula and the concentrations or the dosages, so it’s hard to compare what this formula offers to other supplements featured on our list. While it may provide practical benefits with few downsides, the manufacturer provides limited information to support the claims they make.

    Ingredients Phosphatidylserine St. John’s Wort, N-Acetyl-L-Carnitine, Bacopa Monnieri extract, Vegetable magnesium stearate, Gelatin (bovine), Silicon dioxide, Microcrystalline cellulose
    Key Highlights
  • Treats insomnia and depression
  • Reduces mood swings and ensures better mood patterns
  • Repairs damaged brain cells
  • Reduces everyday stress levels
  • Price $69
    Money-Back Guarantee 60 days

    Memo Defend


    Memo Defend is formulated and made by Thomas Taylor, who has dedicated his career to researching nootropic supplements. This formula is made with all-natural ingredients proven to support cognition in many ways.

    Despite those mentioned above, there are some downsides; most notably, like other brain supplements that are ranked low on our list, Memo Defend offers little information about the ingredients and dosages, as well as lab testing. The core of this formula consists of 620mg of a proprietary blend of Hawthorn leaf, olive leaf, and garlic bulb; however, none of these ingredients have been shown to offer marked cognitive improvements in any noteworthy studies. The most significant element used in Memo Defend is vitamin B12, a well-known vitamin known to be an essential part of a healthy diet and provide various health benefits.

    Ingredients Juniper berry, hibiscus, green tea extract, vitamin C, and niacin
    Key Highlights
  • Reduces aging decline on mental energy
  • Provides rapid recovery from memory loss problem
  • Alleviate mental tiredness and cognitive decline
  • Boost mental and physical performance
  • Price $49
    Money-Back Guarantee 60 days

    Nootropic Supplementation FAQs

    You’ve got questions, and we’ve got answers!

    Q: What is a nootropic?

    A: A nootropic is a supplement, beverage, food, medication, or other product that can be consumed to increase cognitive ability.

    Q: What do nootropics do?

    A: Nootropic supplements support brain function in a variety of ways. Some can boost cognition and memory recall, while others can increase energy and improve mood. Still, others can enhance executive function or even adjust plasticity within the brain.

    Q: How do you take a nootropic?

    A: Taking nootropic supplements is super-easy. You can purchase them online or in stores. They’re sold in capsules, tablets, powders, tinctures, and even as mints and gum. Simply take the supplement as instructed by the manufacturer.

    Q: What is the best nootropic supplement?

    A: Any high raking formulas above are considered some of the best nootropic supplements currently on the market.

    Q: Where does the word “nootropic” come from?

    A: Dr. Corneliu E. Giurgea, a Romanian psychologist, coined the term. The doctor combined three Greek words to develop the word in the 1970s. These words included “noos”, Greek for “intelligence”, “vouc”, Greek for “mind”, and “trope”, Greek for “turning”. Therefore, the word nootropic roughly translates to “intelligence/mind/turner.”

    Q: Are nootropics safe?

    A: All nootropic supplements sold online are made with ingredients Generally Recognized As Safe (GRAS) by the FDA, and these products are legally required to be made with GRAS ingredients. When following the dosage instructions that the manufacturer recommends, it is doubtful you’ll experience safety issues or other severe side effects. However, it’s important to note that you should be mindful when combining nootropics with different types of drugs. You should avoid experimenting with dosages, as doing so could render the supplement unsafe.

    Q: Do nootropics cause side effects?

    A: The side effects are rare and mild. Some of the most common side effects that have been reported include jitters, digestive upset, and headaches.

    Q: What are the benefits of taking a nootropic supplement?

    A: Nootropics boost memory, cognitive function and support the brain’s overall health. Some individuals target a particular issue, such as memory loss, while others want to help their brain health.

    Q: Who would benefit from taking natural nootropics?

    A: Anyone who wants to boost their cognitive health, memory recall, and brain function, including older adults, parents, young professionals, those who work in demanding careers, students, or anyone else who wants to enhance the power and health of their brain.

    Q: How do you purchase nootropics?

    A: You can purchase natural nootropics from online retailers and health food stores. You can even find them at Walmart, Walgreens, CVS, and even your local corner drugstore.

    Q: Are nootropics legal?

    A: Yes, they are legal in all 50 states.

    Q: Are nootropics natural?

    A: Most nootropic supplements contain natural ingredients, such as vitamins, plants, minerals, and herbal extracts; however, some of the used elements are synthetic. Read the label for more information.

    The Top 33 Best Nootropic Supplements for Brain Health Final Thoughts

    Nootropic supplements have been found to offer a wealth of benefits for countless people. Many have seen that they increase their cognitive function, boost their memory recall, and improve their overall brain health. They can also reduce stress and anxiety and even enhance mood.

    Whether you’re concerned about your mental health or you want to ensure that it remains in tip-top condition, nootropic supplements may undoubtedly be able to help you achieve your goals. Try one of the highly ranked products included on our list of the 33 best nootropic supplements today!

    RELATED:Best Adderall Alternative Supplements

    Affiliate Disclosure:

    The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team and please know we only recommend high quality products.


    Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.

    The news and editorial staff of Sound Publishing, Inc. had no role in the preparation of this post. The views and opinions expressed in this sponsored post are those of the advertiser and do not reflect those of Sound Publishing, Inc.

    Sound Publishing, Inc. does not accept liability for any loss or damages caused by the use of any products, nor do we endorse any products posted in our Marketplace.