Best CBD Oil for Anxiety and Depression: Top 6 Brands in 2021

Anxiety is one of the most prominent health conditions in the United States. According to estimates, around 40 million Americans are affected by some type of anxiety disorder, with the number growing exponentially every year. From affecting relationships and work and school performance to your overall health — anxiety can be detrimental in many different ways. Luckily, a natural remedy has emerged as the best CBD oil for anxiety and has proven to be effective in lessening these disorders’ impact on daily life, proposed by Observer.com.

In recent years, CBD has quickly become everyone’s favorite solution to all sorts of medical problems. Depression, migraines, chronic pain, arthritis, and, of course, anxiety are just the tip of the iceberg. The non-psychoactive compound found in cannabis gives users a feeling of tranquility with almost no side effects, something OTC meds aren’t known for.

If you’re wondering what the best CBD oil for anxiety is and whether it can really help you, you’ve come to the right place. We will break it all down for you below, starting with a list of the best oils and ending with a detailed buying guide.

The Best CBD Oil for Anxiety: Our Picks

1. Royal CBD


This CBD brand likes to keep things high-quality but straightforward, which is why it ultimately takes first place on our list. Royal CBD makes full-spectrum oils, CBD-infused topicals, THC-free gummies, and capsules. All products are made from Colorado California-grown hemp using supercritical CO2 extraction, known as the best and safest CBD extraction method.

After the extraction, the CBD is dissolved in MCT oil of the highest quality. Different flavorings are also added to make the oils as tasty as they are effective, including vanilla, mint, and berry. The Royal CBD oil is, as we mentioned, a full-spectrum product, meaning that it contains all the compounds necessary for the entourage effect.

These oils are also highly potent, with 83 mg of CBD per serving for a 2500 mg bottle. A third-party lab is responsible for potency and purity testing, and each test confirms that the oil is made using 100% natural ingredients.

As Royal CBD produces top-quality products, they became very well-known in the online world as well — you’ll find mentions of this brand on leading websites including CFAH, LA Weekly, and more.

The only con we could find when it comes to Royal CBD is the following: it only offers full-spectrum oils, meaning that small traces of THC are still present in the products. If that is a deal-breaker for you, we suggest going with some of our other picks.

Learn More:Best CBD Oil for Sleep

2. Gold Bee


The second best CBD oil for anxiety offers the best organic formula on the market. This brand combines Colorado-grown organic hemp with honey from the Brazilian Rainforest. When it comes to the quality of ingredients used in oil production, this manufacturer is the very best on the market. You can find mentions of Gold Bee in publications such as Seattle Weekly, Herald Net, and others.

This brand is not our first choice only because of the lack of high-potency oils in its catalog. Gold Bee oils offer you up to 40 mg of CBD per 1 mL, which is a lot less potent than Royal CBD. So, these oils are great for less severe cases of anxiety and will indeed help you calm down. However, they are not as successful in treating more serious types of anxiety disorders.

The Gold Bee oil comes in two flavors: natural and kiwi-honey. It is also tested for potency and purity by an independent lab, as are all of the oils on this list.

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3. CBDPure


CBDPure offers full-spectrum oil made with US-grown hemp using supercritical CO2 extraction. Its oils are even less potent than those from Gold Bee: you get 20 mg of CBD per 1 mL of oil. However, CBDPure oils are full-spectrum, which means you won’t need too high a dose to feel the effects.

CBDPure oils only come in one natural flavor, and they are tested by independent labs. So, you can rest assured they are made with ingredients of the highest quality.

If you find that you’re not satisfied with these oils, after all, CBDPure has a 100% refund policy. Just send your order back within 90 days of your purchase, and you will get all your money back.

Learn More:Best CBD Gummies for Pain

4. Hemp Bombs


This company produces 99% CBD isolates, meaning that no other compounds save for CBD are present in the products. Its oils are sourced from European hemp and are 100% organic. The potencies are pretty varied, ranging from 300 mg to 4,000 mg of CBD per bottle.

Isolate oils are a perfect choice if you are already using some meds or supplements for a condition you have. They contain fewer compounds that could potentially interact with those meds and decrease their effectiveness. However, they will also not give you the entourage effect, which you should keep in mind when purchasing them.

Hemp Bombs oils come in two flavors (watermelon and peppermint), and tests by an independent lab confirm their purity and potency.

5. CBDistillery


As one of the veterans of the CBD industry, this brand continues to produce high-quality products. Its oils are all GMO and pesticide-free, and they come in five different potencies.

Another great thing about CBDistillery oils is their price. They are the most affordable choice on our list by far, meaning that you don’t have to spend a lot to get a superb product for your anxiety.

This brand offers both full-spectrum and THC-free oils, and all of them are lab-tested. However, these products are not organic, which is a deal-breaker for many.

Learn More:Best CBD Gummies for Sleep

6. NuLeaf Naturals


This manufacturer has been in the business for over five years, and it has built up an excellent reputation. NuLeaf makes its oils from organic hemp using CO2 extraction, and they are 100% organic.

You can get these oils in five different volumes ranging from 5 mL to 100 mL bottles, each with the same potency (48 mg of CBD per 1 mL). An independent lab tests all NuLeaf Naturals products for purity and potency, assuring that their quality is excellent. These oils are, however, much more expensive than the other choices on this list.

Learn more:Best CBD Capsules Reviewed

CBD: A Crash Course

Now that you know our picks for the best CBD oil on the market, it is time to talk about what CBD actually is and how it can help with anxiety.

As what We Be High stated, CBD is the non-psychoactive compound in cannabis. CBD serves as a modulator of the endocannabinoid system, which keeps the balance in many of the body’s systems. But apart from helping this system run, it also affects certain neurotransmitters that make us overstimulated. This function is what makes it an excellent remedy for anxiety.

You can use CBD in numerous ways, from tinctures over capsules and gummies to topicals. However, the most popular and effective ingestion method seems to be taking CBD oil. When you look at all the benefits, it becomes clear why that is the case.

Firstly, consuming CBD through oils is the easiest method out there. You just use the built-in dropper to measure the amount of oil you need, and you’re good to go. Secondly, your body absorbs CBD the fastest if you take it through the liquid. That means that almost no CBD is lost in the process of absorption, which cannot be said for other ingestion methods.

Finally, the two reasons above lead to the conclusion that you need to take smaller doses of CBD to achieve the effects you need. With other CBD products, you would need much larger amounts to do the same.

Anxiety: Causes and Traditional Treatment Options

Put simply, anxiety is the feeling of general discomfort and worry that gets so severe it causes physical changes. These changes include labored breathing, nausea, panic attacks, sweating, etc.

Anxiety started out as a necessary response to danger. Basically, it helps you identify potential threats and react to them on time. However, the stress and speed of modern life have made anxiety something much more dangerous than helpful.

Nowadays, people feel anxious about work, money, and personal relationships, and these feelings can get so intense they become debilitating. In such cases, they might develop into a disorder, and disorders have to be treated with some sort of meds.

Treatment for Anxiety

The most common meds used to treat anxiety are the so-called benzodiazepines. These meds bind to the receptors in the brain that reduce overstimulation and help them be more efficient. That, in turn, helps you feel less anxious and stressed. However, there is a catch: these meds are highly addictive.

After a certain time, your body will become used to the meds, and you will need to up your dose to feel the same effects. When you reach the maximum dose you can take, you will become dependent on it to keep the anxiety at bay. Without the meds, you will be in a constant state of panic, and nothing other than them will be able to help.

In addition to their addictive nature, anxiety meds also cause a vast number of side effects, including:

  • Nausea
  • Insomnia
  • Weight gain
  • Cardiac diseases
  • Agitation
  • Dizziness
  • Constipation

How Can CBD Help With Anxiety?


The research into how CBD might help with anxiety has, so far, been scarce. However, every study shows that it indeed has potential in treating different anxiety disorders. What’s more, thousands of testimonials from CBD users all around the globe also confirm CBD’s effectiveness.

Here is what research has confirmed so far:

CBD Increases Serotonin Levels

Serotonin is the hormone in your body responsible for maintaining your mood, concentration, and sleeping pattern. As such, it has a direct impact on your anxiety which increases if there is a lack of the hormone in your system.

CBD’s role is simple. It stimulates serotonin receptors, making you feel lighter, happier, and improving your concentration.

CBD Helps the Production of Anandamide

Anandamide, also known as the bliss molecule, is closely related to feelings such as euphoria, joy, and an overall sense of relaxation. When its levels are down, you have less energy, and you feel depressed and anxious.

The best CBD oil for anxiety enhances this molecule’s activity by preventing your body from breaking it down and metabolizing it. That way, the anandamide levels in your brain stay normal at all times, keeping you happy and relaxed.

CBD Stimulates Some Parts of the Brain

Certain parts of the brain, namely the hippocampus, are closely related to elevated anxiety. A lot of therapy aimed at decreasing anxiety levels seeks to help the brain produce new neurons in the hippocampus area. Some studies show that CBD could be helpful in this area.

CBD Stimulates GABA Receptors

As we mentioned earlier, the best CBD oil for anxiety also interacts with specific receptors in your brain that help keep you calm. They are called GABA receptors, and their role is to keep any anxious feelings in check.

CBD binds to your neurons and helps GABA receptors decrease their activity, thereby calming you down when you are agitated. So, we can say that CBD helps these receptors be more active and efficient, which is what most OTC anxiety meds aim to do.

What to Look for In the Best CBD Oil for Anxiety

1. Hemp Source

Hemp absorbs everything from the soil it grows in, meaning that the soil needs to be healthy and toxin-free. Thus, the best CBD oil for anxiety is made out of domestically grown organic hemp. US farmers have to abide by strict laws and standards, so their soil and production process is always top-notch.

2. Extraction Method

The best and safest CBD extraction method is supercritical CO2 extraction. This method gives you pure and potent products with no toxins and residue of any kind. Subcritical CO2 extraction is also a good choice. However, stay away from extraction methods that use solvents, as they aren’t as safe.

3. Full-Spectrum Vs. Isolates

Which type of CBD oil you will choose mainly depends on your reason for using it in the first place. If you want to feel the entourage effect aside from decreasing your anxiety, full-spectrum oil is the way to go. However, if you don’t wish to have any traces of THC in your system and you simply want a high dose of CBD, isolates are a much better choice.

4. Additives

The best CBD oil for anxiety contains two main ingredients: hemp extract and carrier oil. Any other ingredients are there to make the oil taste better and to enhance its calming effect.

Read the list of additives that your oil contains carefully before buying it. Make sure all the additives are natural and that you are not allergic to any of them.

5. Lab Tests

Verifying a CBD product’s credibility and quality is easy: you have to look at whether an independent lab has tested it. This lab report will include all the ingredients, the potency, and info about any potential impurities.

If a company is open about its production process and lets a third-party lab test its products, they have nothing to hide. Always opt for such suppliers, and you will have nothing to worry about.

To Conclude

As anxiety disorders become a more significant and worrisome problem every day, looking for natural remedies has become a priority. Luckily, CBD has emerged as a perfect solution with almost no side effects and great success in tackling the problem at its root.

Hopefully, our list helps you learn everything you need to find the best CBD oil for anxiety. Do extensive research, never settle for anything other than a top-notch product, and you should be fine. Good luck!

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