11 Best Nerve Health Supplements for Natural Pain Relief (2021)

Neuropathy pain is a health condition that can ruin the state of healthy nerve cells. Severe neuropathic conditions can even cause the death of nerve cells. And people develop this health condition for various reasons.

Due to that, there has been a rise in neuropathy supplements on the market. And as some of our members were facing the symptoms of nerve damages, we decided to get one of the best nerve supplements.

Getting that was not easy. We purchased a couple that worked just like a placebo.

Then, we went to interview health and nutrition experts. And after getting to know about the crucial factors, we managed to purchase the Neuropathy Supplements that can promote healthy nervous system function.

The 12 Best Neuropathy Supplements in 2021

As we have mentioned, getting effective nerve pain supplements that are worthy of purchase was not easy.

But after loads of testing and researching, we did manage to find a couple that works. So, let us not waste any more of your precious time and get right into reviewing those:

  • Nerve Control 911
  • Nuturna Maximum Strength Neuropathy Support Formula
  • Nervala
  • Nerve Renew
  • Nerve Rejuv
  • Nervexol
  • Circle Labs CBD
  • Nuturna Clinical Strength Neuropathy 900
  • Neuro Calm Pro
  • Nervogen Pro
  • Neuropathy No More
  • Neuropathy Revolution

Nerve Control 911

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When it comes to offering supplements that work as pain medication, PhytAge Labs has a good amount of reputation. And they are now in the market offering nerve health supplements as well. So, we had to check it out.

According to the manufacturer, Nerve Control 911 can target the nerve pain linked to diabetics and other health conditions. And we did find that their formula is highly capable of offering relief from nerve dysfunction. The reason behind this efficacy is because the ingredients focus directly on the source.

On that note, the formula contains nothing but natural ingredients. Those provide a real punch on the neuropathy. They can improve the body’s muscles, help transmit the information from the central nervous system to the rest of the body, enhance the control over voluntary movements and reflexes, and reduce inflammation.

Many believe that these effects are something that can only be gained when doctors diagnose neuropathy. But PhytAge Labs has proved that you do not need to rely on those methods. You will get the same effects that you would achieve when doctors treat neuropathy.

Due to these beneficial effects, the brand promotes its supplements as the miracle root. And we do not see anything wrong with their claim. It can indeed improve nerve function and can effectively relieve nerve pain. Their formula also works like a charm in terms of offering relief from muscle pain.

Key Highlights

  • Utilizes competent formula
  • It offers a real punch on the neuropathy
  • Capable of reversing nerve damage
  • Improves the condition of sensory nerves
  • Lowers neuropathy pain

Nuturna Maximum Strength Neuropathy Support Formula

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Nuturna is offering one of the internet’s best-selling nerve pain supplements, the Neuropathy Support Formula. And to know what makes it so different from the other nerve pain supplements, you need to go through this entire review.

First and foremost, the neuropathy supplement is highly accessible. You can get one of these bottles through major retailers. But the real question is, what makes it so effective? Well, the primary reason is the formula. The brand has perfected the blend to improve nerve function efficiently.

Now, you might be wondering what this formula contains. Well, the brand is transparent about it. The blend consists of benfotiamine, alpha-lipoic acid, turmeric, L-arginine, and other natural extracts. All of these elements can target the nerve function and properly reverse the nerve damage.

On that note, you will not even have to spend that much cash on getting this potent neuropathy support formula. And even though it is affordable, the brand did not skimp one bit in terms of the elements. The blend contains 600mg of alpha-lipoic acid, which is considered to be a strong dosage.

Additionally, there are 18 different vitamins, minerals, and herbs. All these ingredients have gone through various clinical trials, where they proved their effectiveness. And as this formula contains the right ingredients in the proper dosages, it can work like a charm in relieving pain related to neurology.

Key Highlights

  • Highly accessible
  • It contains 600mg of alpha-lipoic acid
  • The formula has gone through multiple clinical trials
  • Affordable
  • Contains mineral, vitamins, and other herbs


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This neuropathy supplement from Barton Nutrition is promoted as the secret to getting rid of numbness, neuropathic pain, and tingling. And this claim is something that a regular supplier would make. For that reason, we decided to test it out. And we are glad that we did!

Nervala mainly targets inflammation throughout the entire body. That includes the spinal cord as well. It has unique ingredients that will clear away the free radicals and support the immune system properly. After that, the system will do its work in terms of relieving nerve pain and related pains.

In addition to that, the supplement works exceptionally well in terms of “cooling down” the nerves. It will protect your entire nervous system from “overheating,” which usually causes nerve pains. Also, as the ingredients will clear out the free radicals, no inflammation or oxidation will occur on the nerve cells.

As the ingredients will support a healthy inflammation, people with diabetic nerve pain will also see an improvement. After taking the supplements daily, the elements will work like a charm to relieve chronic neuropathic pain. It will provide all the benefits that physical therapy would provide.

On that note, the formula contains two key ingredients. One is alpha-lipoic acid, and the other is benfotiamine. The alpha-lipoic acid is at 600mg, while benfotiamine is at 75mg.

Key Highlights

  • Targets inflammation throughout the entire body
  • Can clear free radicals
  • “Cools down” the nervous system
  • It contains alpha-lipoic acid and benfotiamine
  • Provides relief from chronic neuropathic pain

Nerve Renew

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The Nerve Renew is another advanced nerve support supplement that contains loads of active elements. And due to how well the brand promoted its formula, it is one of the top sellers of neuropathy supplements.

Now, the real question is, what does the formula contain? Well, it has loads of vitamins. The formula has vitamins B1, B2, B12, B6, D, and many others. Due to being rich in vitamins, the body will not take that much time to absorb the capsules, which is why this nerve health supplement can offer quick results.

Additionally, Nerve Renew floods the body with antioxidants. For that reason, it will be highly effective in reversing the nerve damage that oxidations usually cause. Also, the ingredients can properly offer pain relief, relief from numbness, and comfort to the discomfort regions.

Furthermore, the formula consists of alpha-lipoic acid and amino acid. This ingredient is well-known for offering relief from neuropathy. Also, you will not even have to flood your body with these pills to get all the benefits we have mentioned. Just two capsules a day will be more than enough.

Alongside that, the unique delivery mechanism of Nerve Renew can even offer a natural energy boost. And it takes care of the tingling sensation exceptionally fast.

Key Highlights

  • Effective at treating neuropathy
  • Quickly absorbed by the body
  • Can increase physical and cognitive energy
  • Capable of quickly toning down the symptoms of neuropathy
  • Antioxidant and amino acid included

Nerve Rejuv

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One of the competing neuropathy supplements that are targeted towards older adults is the Nerve Rejuv. And Golden 50 has done a proper job in perfecting the formula in that criteria.

Even though the formula is targeted at older adults, it does work for everybody. It targets the nerve endings and regenerates them. And that will help with the pains that are associated with neuropathy. The minerals will also support the motor nerves and offer quick pain relief.

Other than that, the formula also relies on alpha-lipoic acid, organic turmeric root, and other natural elements. And all of the ingredients that the blend utilizes can provide relief from numbness, pain, and tingling sensations related to diabetic neuropathy and chronic neuropathy.

Furthermore, the blend has amino acids along with other herbal extracts. Those will soothe the nerve pains in multiple ways. You will notice an instant improvement in terms of nerve pain severity and will be able to carry on with your day without facing any significant discomfort.

Apart from reversing nerve damage and lowering neuropathy symptoms, the formula can even help with shingles, fibromyalgia, and other medical conditions. So, it is not just a diabetic nerve pain supplement; it can also offer other health benefits, such as helping with kidney and liver diseases.

Key Highlights

  • Targeted at older adults facing diabetic neuropathy
  • Can tone down diabetic nerve pain properly
  • The formula includes antioxidants and amino acids
  • Capable of lowering severe neuropathy symptoms
  • Reverses nerve tissue damage


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Are you looking for supplements for neuropathy that can eliminate and lower nerve pain quickly? Well, you might be looking for something like Nervexol.

First of all, the formula of Nervexol contains coenzyme Q10, calamarine, vitamin B1, alpha-lipoic acid, and many more active ingredients. The highlighting element in this list is calamarine. It is a type of deep-sea squid that is found on the coast of South Africa. And they are rich in omega-3 fatty acids.

Now, you might wonder what omega-3 fatty acids have to do with neuropathic pain. Well, they can support the health of the brain, eyes, and joints. And when the brain is in a top-notch condition, the nervous system will function optimally, lowering the intensity of nerve pain.

Furthermore, adding calamarine to the formula made Nervexol offers additional benefits. It can eliminate nerve pain exceptionally fast, which is not that common among other nerve health supplements. That makes the supplement highly capable of treating neuropathy. It can also help with autoimmune disorders.

In addition to that, calamarine can help with sleeping disorders. It will nourish the nerve cells and offer the comfort that the body requires for a peaceful sleep. The ingredient also effectively relieves the body from severe chronic peripheral neuropathy.

Key Highlights

  • Rich antioxidants and vitamins
  • Capable of reversing nerve damage
  • Ensures that the nervous system is working optimally
  • It contains omega-3 fatty acids
  • Helps with sleeping disorders

Circle Labs CBD

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Peripheral neuropathy can be exceptionally painful sometimes. And Circle Labs acknowledged that is why they have the power of CBD in their offering.

To start with, the brand is offering a load of products that involve CBD. You will find tinctures, balms, and creams that are primarily for diabetic nerve pain. And due to including CBD, their formula holds a higher power of offering relief from diabetic peripheral neuropathy.

On that note, the CBD works directly with the body’s endocannabinoid system. That includes the CBD2 and CB1 receptors. These receptors are present all around the cells of the body. And after interacting with these receptors, the CBD can offer quick relief from diabetic neuropathy.

In addition to that, if you take their neuropathy supplements regularly and apply their creams and oils, it would be possible to lower the neuropathy symptoms significantly. They will even work like a charm in terms of restoring nerve function and improving the nervous system.

Moreover, the CBD found in the formula is about three times stronger than regular pain creams with CBD. For that reason, this blend holds a higher power of treating neuropathy in a small amount of time.

Key Highlights

  • Can relieve neuropathy quickly
  • It contains a unique formula with CBD
  • Helps with peripheral neuropathy
  • Capable of lowering neuropathy symptoms
  • Improves the nerve function

Nuturna Clinical Strength Neuropathy 900

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Another neuropathy supplement that is from Nuturna is the Clinical Strength Neuropathy 900. Like the previous one that we looked at, this one is also among the best-selling neuropathy supplements in the market. And in this review, we will state exactly why.

Like the previous supplement from Nuturna, this peripheral neuropathy is also available on the shelves of major retailers. That means you will not have to go through any hassle in getting your hands on one of these bottles. And the bottles come at an affordable price point as well.

Other than that, this peripheral neuropathy supplement contains a formula of potent ingredients. It has L-carnitine, L-arginine, organic turmeric root, and other herbal and plant extracts. All of them increase the formula’s ability to tone down symptoms of neuropathy and pain related to diabetic peripheral neuropathy.

Additionally, most of them are of clinical strengths. In other words, the quantity of each of the 18 elements is at the right level. And along with offering relief from nerve pain, they hold the ability to boost the immune system. After that, the body will be capable of fighting against other diseases efficiently.

Lastly, it has the right strength of ALA. The clinical trials suggest around 300mg to 900mg per day. And as it fills the body with the right amount of ALA, peripheral neuropathy and diabetic neuropathy can be a thing of the past if you take the supplement regularly.

Key Highlights

  • Available through major retailers
  • The dosages are according to the clinical tests
  • It contains loads of herbal and plant extracts
  • Capable of boosting the immune system
  • Offers other health benefits

Neuro Calm Pro

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The Neuro Calm Pro is the first neuropathy supplement on this list that targets the ears. And it can effectively treat neuropathy and offer loads of beneficial effects by doing so.

This specific supplement supports nerve health by offering the body the right ingredients. Those elements can soothe the damaged nerves and offer relief from irritation. And after the nerve cells get relief from the paint, it will start healing naturally.

Apart from that, as the formula can effectively offer the benefits of a tinnitus supplement, it will also provide other health benefits. It contains saw palmetto, fenugreek extract, wild yam, and L-tyrosine, which are highly capable of offering relief from tinnitus.

Additionally, the ingredients do a proper job of soothing the tingling and numbing feeling that people with diabetic neuropathy face. And after taking the supplement regularly, one can eliminate the neuropathic symptoms. Also, it will strengthen the immune system and make it less vulnerable to diseases.

Finally, the brand bundles its offering with a suitable therapy protocol. That will help enhance the effects of the supplement and will quickly soothe irritated nerves.

Key Highlights

  • Targets the ears
  • Effectively offers relief from neuropathic pain
  • Can help with tinnitus
  • Soothes tingling and numbing sensations
  • Bundles with a sound therapy protocol

Nervogen Pro

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Last but not least, we have managed to find out a unique supplementation for neuropathy. And if you want to know about the things that make it unique, you need to continue reading.

The first thing that makes Nervogen Pro out is the strength of the ingredients. It contains loads of ingredients. But most of them are at comparatively low doses. However, as it had loads of active elements, it still holds a higher capability of helping with diabetic neuropathy.

The five essential elements are prickly pear extract, California poppy seed extract, corydalis, marshmallow root, and passionflower. These are pretty unique elements and not usually found on the other neuropathic supplements we have stumbled upon.

Even though the ingredients are not that common, they do hold power to offer relief from neuropathic pains. They will work together and provide fast relief from the tingling and numbing sensation that most people with diabetic neuropathic problems face.

Furthermore, all of the ingredients are high in quality. That premium nature of the elements further enhances the efficiency of the formula.

Key Highlights

  • Contains unique elements
  • Holds a higher power of offering relief from nerve pain
  • Capable of providing quick relief from tingling feelings
  • Has passionflower extract
  • Effectively soothes the numbed nerves

Best Nerve Pain Guide Reviews

Most people get relief just by taking neuropathy supplements. However, many will enhance the effects of the supplements by following other treatment plans. And these guides offer information regarding those effective plans:

Neuropathy No More

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The first nerve pain guide that we have is from Blue Heron Health News. They have released an eBook called Neuropathy No More. The author, Jodi Knapp, goes through the idea that many people believe.

Wondering what idea are we referring to here? Well, it is nothing but “neuropathy is a choice.” The book goes through different protocols that can purportedly help with pain related to neuropathy. And most of the protocols that it went through helped many people master stress management techniques.

This nerve pain guide also offers insight regarding the change of lifestyle that will support nerve health. It even has pieces of information about diet changes. The diet includes foods that target neuropathy and quickly offer relief from the pain, which many neuropathy supplements fail to deliver.

The neuropathy treatment program also addresses the patients undergoing chemotherapy. However, unlike the supplements for neuropathy, these protocols are not for everyone. But the good news is that a money-back guarantee backs the book. So, you can get a full refund if you see any improvements.

Key Highlights

  • It goes through different protocols.
  • Offers advice regarding the required lifestyle changes
  • Provides guidelines regarding the proper diet
  • Backed by a money-back guarantee
  • Helps with managing stress

Neuropathy Revolution

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Most of the neuropathy books claim that it does not provide medical advice. But they do claim that their guides offer relief from severe levels of neuropathy pains. Well, Neuropathy Revolution takes this a step ahead and claims that its guide can provide relief in 30 days.

It is a pretty well-known fact that none of the guides should be considered as sound medical advice. However, it is worth giving these pain relief guides a try before getting treatment for the underlying cause or opting for a neuropathy surgery.

According to the authors, the seven holistic protocols that Neuropathy Revolution goes through can end chemotherapy-related neuropathy. Even though we cannot say much about chemotherapy-related neuropathy, we can say that it does have practical guides that can offer relief from the pain in 24 hours.

That is not all; it has guides that calm the levels of pain and lower its severity. They even bundle this with an eBook called Diabetes Protocol. That makes the whole package offer a stellar overall value for the money.

Key Highlights

  • It contains seven holistic strategies
  • Bundles with an additional diabetic guide
  • Stellar value proposition
  • The guides can offer quick relief from the pain related to neuropathy
  • Provides a money-back guarantee

How We Ranked The 12 Best Neuropathy Supplements

Every supplement will claim that it will lower all of the symptoms and give you complete relief from neuropathy in a matter of days. But does each of them deliver that promise? Not really! For that reason, we considered these crucial factors while ranking the supplements:

Clinical Formula

As you know by now, neuropathy affects more than millions worldwide. For that reason, there have been loads of tests regarding the ingredients that the manufacturer usually utilizes. Researchers have spent decades trying to find out the elements that work to provide relief from neuropathy.

That being said, we preferred the supplements that utilized the well-tested and heavily researched elements in their formula. The ones that included most of these ingredients, the higher the ranking they got.


Just utilizing the correct elements will not do any work in providing fast relief from neuropathy pains. The formula needs to use the right dose of those elements. We have even stumbled upon some options that had loads of effective ingredients but were not that efficient at all. We did not put them on our list.

Instead, the ones that had the correct elements at the right strength got most of our preferences. We ranked the ones that followed the clinical doses higher in our list.

Honest Advertisement

The advertisements of the manufacturers tell a lot about their products. If a brand promoted its supplements by stating that they can offer unnatural benefits, we did not consider them. These will not provide a solution to each of the health problems that you might have.

We stumbled upon such options that claimed to cure every illness and prevent every disease in the future. Instead of wasting our time testing them, we focused on legitimate claims about the benefits.

Transparent Labels

Another thing that is quite important about the manufacturers is transparency. The higher the amount of clarity, the more information you will get about the blends. And we did prioritize the highly transparent ones because those made it easier for us to scrutinize the effectiveness.

The Reputation of the Brand

There are plenty of suppliers out there that will disclose little to no information about themselves. And as you might have guessed, that is pretty sketchy. And we believe every consumer has the right to know all about the manufacturer and where they are located.

That is why we prioritized the supplements that were from well-reputed brands. These well-reputed brands usually tend to offer high-quality products to maintain their reputation in the industry. Furthermore, some will even go a step forward and offer a money-back guarantee, which is a cherry on the top.

Proven Benefits

As you know by now, not all neuropathy supplements work. But all of them will claim that they do. A regular customer will not usually go through the hassle of researching and going through each formula’s ingredients.

Considering that, we prioritized the brands that provided test results regarding their formula. That makes it easier for an average customer to scrutinize the offerings properly. And the more in-depth the evidence was, the higher the ranking they got in our list.

Medical Advisory Board

Usually, the high-end brands will have a medical advisory board that will include naturopathic doctors, medical doctors, and certified nutritionists. And this advisory board usually strengthens the effectiveness of the formula. Also, this ensures that the blend contains the right ingredients at the right amount.

Price and Value

Last but not least, we considered the value proposition. Each of the supplements that we have tested had a varying price point. Some were within the $50 mark, while many were within $100. Instead of looking at the price, we considered the overall value proposition.

So, the higher the value proposition a supplement offered, the higher the ranking they got on our list.

Scientific Evidence of Neuropathy Supplements

There are plenty of supplements out there that have gone through clinical trials. Also, loads did not bother about going through these tests at all. Nonetheless, we did find the results of the ingredients that researchers have spent decades studying. And we will discuss all of that information in this segment.


This element is pretty popular among the supplements, and there is a good reason for that. Your kidneys and liver can naturally produce acetyl-l-carnitine. However, if those organs are not healthy, they will not make the required amount of this chemical.

Nonetheless, this element can support overall physical and cognitive health. According to different studies, it can boost energy significantly. Also, this review proved that the ingredient could improve the nerve function of people with diabetic neuropathy.

B Vitamins

Most of the supplements will contain vitamins and minerals. And B vitamins are probably the most common vitamins that those formulas will rely on. In this study, researchers have found that when the body lacks B12, the health is most likely to suffer from dysfunction of nerves and other related issues.

Vitamin B6

The same study that involved B vitamins also included vitamin B6. Researchers have analyzed that the deficiency of this vitamin can lead to burning sensation or numbness on the feet. This deficiency can even lead to a tingling feeling on the hands.

Alpha-Lipoic Acid

Multiple supplements that are for neuropathy contain ALA. It is an antioxidant-like chemical that has gone through loads of studies. Some studies have proved that the ALA can quickly relieve the burning sensation and stabbing pain associated with neuropathy.

Furthermore, in this 2006 study, researchers gave participants various dosages of ALA. Some had 600mg, while the others had 1200mg or 1800mg each day. Also, some only had a placebo. After five weeks, the patients who took the real deal reported fewer neuropathy symptoms.

In comparison, the ones that had a placebo did not see any benefits at all. However, the participants that took higher dosages did notice some side effects.

Moreover, this study that carried out the same test proved that 300mg of ALA could increase blood flow and reduce the overall inflammation in the body. It can also increase the overall blood flow on the upper arm, which is the key area where people with neuropathy feel the most pain.


Numerous studies have proved that magnesium can help with neuropathy. According to the Foundation for Peripheral Neuropathy, this ingredient has shown more evidence of helping with chemotherapy-related neuropathy. However, they did caution us that a large scale of testing and research is still needed.

Alongside that, this study had published that the patients who were undergoing chemotherapy had fewer symptoms of neuropathy when the treatment involved a higher amount of magnesium. So, it suggests that magnesium can impact neuropathy in some way.


The most abundant amino acid in our bodies is glutamine. Studies showed that it could help with specific types of neuropathy. And it offers all those benefits by targeting muscle pain, tingling, numbness, and inflammation. That is why most neuropathy supplements are going to contain this ingredient.

Moreover, this review study has proved that glutamine can help reduce or eliminate the severity of neuropathy in patients going through chemotherapy.


One of the antioxidants that are found in a wide range of supplements is glutathione. Early researchers have found that this element can help with different types of neuropathy, including diabetic neuropathy. It even helps in terms of lowering the severity of symptoms in other related conditions.

Frequently Asked Questions About Neuropathy Supplements

Q: Is there any difference between polyneuropathy and mononeuropathy?

A: Yes, there are differences between both terms. In polyneuropathy, multiple nerve cells are affected, while only a single nerve cell is involved in the case of mononeuropathy. And the symptoms that are faced by patients having mononeuropathy are less severe than polyneuropathy.

Q: What are the symptoms of neuropathy?

A: The most common symptoms are pain, burning sensations, tingling, numbness, and weakness on both the feet and hands. In severe cases, patients with neuropathy will experience these symptoms going further up the legs and arms. If you have ever felt ‘pins and needles,’ these symptoms will feel similar.

Q: What causes neuropathy?

A: Neuropathy will occur when the nerves are destroyed or damaged. The nerves send the signals from your body to your brain. When this communicational bridge is destroyed, your brain will get confusing impulses, which cause numbing, tingling, and pain.

On that note, there are cases where people with a broken or dislocated bone faced similar neuropathy symptoms.

Q: How can one treat neuropathy?

A: First, one needs to opt for a physical and neurological exam to determine the severity of the nerve damage. Many physicians might even recommend taking a nerve conduction velocity test.

After scrutinizing the body’s overall condition and nerves, the doctors will provide medical advice or recommend a neuropathy surgery.

Q: What are the most common causes of neuropathy?

A: As you know by now, nerve damage is the primary cause of neuropathy. However, nerves get damaged in plenty of different ways. Physical injury in any specific region can cause neuropathy. The same goes for repetitive movement for a prolonged amount of time. Additionally, diabetes can even cause neuropathy.

Q: What is Carpal Tunnel Syndrome?

A: Carpal Tunnel Syndrome is a type of neuropathy. It occurs because of repetitive movements for a prolonged amount of time. And repetitive motions can cause significant damages to the nerves. Also, when the movements are carried out incorrectly, the nerve damages can be pretty severe.

Q: Why does neuropathy feel different for different people?

A: The reason why neuropathy feels different for different people is that it is a complex disease. It affects people in different ways. Additionally, it will depend on how the brain is handling those confusing signals. The better the brain manages these disrupted signals, the less severe the pain and symptoms will be.

Q: How painful is neuropathy?

A: As we have mentioned earlier, it will vary from one person to another. It will depend on the severity of the damage and the condition of the brain. When the nerves get damaged, it sends disrupted signals to the brain. And if the brain cannot handle those disrupted signals properly, the symptoms will be severe.

Q: Is neuropathy a genetic disease?

A: There are about 100 different types of neuropathy. And there could be even more with time. However, among all of the variants that are identified till now, only one is genetic.

The 12 Best Neuropathy Supplements in 2021 Final Words

Neuropathy affects about 70 percent of diabetics at a degree of severity. And due to how common the medical condition is, it can become challenging to choose the best nerve supplements.

However, we can assure you that all of the supplements we have gone through will offer nothing but immediate benefits. All of them went under heavy scrutinization and were tested heavily. So, you can pick the one that meets your budget and offers the help you are looking for with complete confidence.

RELATED: Nerve Renew Reviews: Does It Work? Find Out the Truth

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