Clinica Naturals Total Sleep Restore Reviews – Does It Work?

Total Sleep Restore, Clinica Naturals’ flagship product, uses natural ingredients to help you fall asleep faster and get a more restful sleep. Clinica Naturals, a nutritional supplement company found online at ClinicaNaturals.com, is the only place you can find Total Sleep Restore.

Keep reading to discover everything you need to know about Clinica Naturals and how Total Sleep Restore works today in our review.

What is Clinica Naturals?

Clinica Naturals is a health and wellness company founded in Delaware in 2020. The company is registered in Delaware but maintains its main mailing address in San Antonio, Texas.

Clinica Naturals was founded with the goal of creating “integrative supplements that “target the root cause” of health issues, according to the official website. By taking Clinica Naturals supplements daily, you can target common symptoms and lead a healthier, happier life.

Clinica Naturals currently offers one doctor-endorsed supplement: Total Sleep Restore. The supplement was formulated by Dr. Mark Menolascino, MD, the Director of the Meno Health Clinic in Wilson, Wyoming. Today, Dr. Mark and the Clinica Naturals team aim to create more supplements targeting common health issues.

Clinica Naturals Supplements

Clinica Naturals currently offers a single supplement: Total Sleep Restore. Formulated by Dr. Mark of Clinica Naturals, the supplement uses natural ingredients to help you wake up feeling refreshed and alert.

It’s possible Clinica Naturals will launch more supplements in the future. The company was founded with the goal of creating products to target the root cause of common symptoms.

Total Sleep Restore

Priced at $50 per bottle, Total Sleep Restore contains a blend of natural ingredients to help you reach the deepest, most restorative part of sleep.


By taking Total Sleep Restore nightly, you can wake up feeling refreshed, alert, and ready to the day, according to Clinica Naturals.

Total Sleep Restore is also a genuinely doctor-formulated supplement: the supplement was developed by Dr. Mark Menolascino, MD.

The 7 active ingredients in Total Sleep Restore include:

Magnesium: A vital mineral for improving sleep time and efficiency, magnesium plays a crucial role in rest and relaxation of the nervous system.

Ashwagandha: A popular adaptogen linked to rest, relaxation, and stress response, adaptogen has been used for centuries for stress relief in traditional Ayurvedic medicine.

L-Theanine: A plant-based chemical found in green tea, L-theanine is linked to anxiolytic effects, rest, and mental relaxation.

GABA: Gamma aminobutyric acid, or GABA, has been shown to decrease the time it takes to fall asleep.

Resveratrol: One of the most popular supplement ingredients available today, resveratrol has antioxidant effects and is found naturally in wine and grape seed extract.

Melatonin: One of the world’s most popular sleep aid supplement ingredients, melatonin can help improve sleep quality by kickstarting your sleep/wake cycle and raising melatonin levels in your body.

Piperine: Piperine, or black pepper extract, is used in Total Sleep Restore to boost the absorption of other ingredients.

Clinica Naturals discloses all ingredients and dosages upfront. The formula contains 3mg of sustained release melatonin, for example, along with 125mg of ashwagandha, 100mg of L-theanine, 100mg of GABA, 100mg of resveratrol, and 20mg of magnesium. All active ingredients are packed into a vegetable (hypromellose) capsule.


Clinica Naturals recommends taking two capsules of Total Sleep Restore nightly. The formula encourages you to enter the deep, restorative, Level 4 stage of sleep. At the Level 4 phase, your body flushes out toxins, rebalances hormones, and performs other crucial tasks to rejuvenate your body.

Scientific Evidence for Clinica Naturals

Clinica Naturals cites 6 studies supporting the advertised benefits of its flagship supplement, Total Sleep Restore. Those studies show many of the ingredients in Total Sleep Restore can help you fall asleep, enjoy a more restful sleep, and wake up feeling refreshed.

Clinica Naturals’ Total Sleep Restore is also endorsed by Dr. Mark Menolascino, a board-certified medical doctor with 30 years of experience in functional medicine.

We’ll review some of the scientific evidence supporting Clinica Naturals below.

First, Clinica Naturals cites this study on magnesium. In the study, researchers gave magnesium or a placebo to 46 elderly adults. Researchers found participants in the magnesium group improved subjective measures of insomnia, with noticeable improvements in sleep efficiency, ISI score, sleep time, sleep onset latency, and early morning awakening, compared to a placebo. Participants took 500mg of magnesium for 8 weeks, which is much higher than the 20mg dose used in Total Sleep Restore.

Clinica Naturals also cites this 2019 study analyzing the safety and efficacy of ashwagandha, one of the key ingredients in Total Sleep Restore In the study, researchers gave 300mg of ashwagandha root extract or a placebo to a group of people, then analyzed their sleep efficiency. Researchers found ashwagandha significantly improved sleep onset latency, total sleep time, and sleep efficiency, among other metrics. Participants took ashwagandha for 10 weeks. Total Sleep Restore contains approximately half of the dose of ashwagandha used in this study (125mg compared to 250mg).

L-theanine could help you fall asleep, which is why it plays an important role in Total Sleep Restore. L-theanine has been shown to increase alpha wave activity, which could help relax the mind without causing drowsiness. Because of this effect, L-theanine could be a beneficial way to attain mental alertness while also helping your mind relax.

Other science-backed ingredients in Total Sleep Restore include resveratrol. In one study, researchers found resveratrol improved memory performance, brain connectivity, and glucose metabolism in older adults. Although researchers did not analyze the sleep-inducing effects of resveratrol, they did conclude it could have significant anti-aging benefits.

Some studies indicate melatonin can help you fall asleep, while others find melatonin has little impact. Some people take melatonin semi-regularly to help fall asleep, while others experience little benefit. In this study cited by Clinica Naturals to support Total Sleep Restore, researchers found melatonin could help sleep efficacy in some people, although it had little impact in others – like shift workers.

The final study cited by Clinica Naturals to support Total Sleep analyzes the bioavailability of resveratrol when combined with piperine, or black pepper extract. Research shows you can enhance the bioavailability of resveratrol by combining it with piperine. Total Sleep Restore contains both ingredients, and research suggests it may be easier for your body to absorb as a result.

Overall, Clinica Naturals makes science-backed, doctor-endorsed supplements while citing peer-reviewed scientific evidence supporting their claims.

About Dr. Mark Menolascino

Clinica Naturals is led by Dr. Mark Menolascino, MD. Known as “Dr. Mark,” he is the Director of the Meno Health Clinic in Wilson, Wyoming.


Dr. Mark has practiced functional medicine for over 30 years. Today, he continues to work with patients to solve the root cause of ailments. Instead of simply prescribing medicine to target symptoms, Dr. Mark takes a holistic approach to address root causes.

Dr. Mark is board-certified in four fields of medicine, including internal medicine, holistic medicine, advanced hormone management, and anti-aging. In addition to holding an MD from the University of Nebraska Medical Center, Dr. Mark has a Master’s degree in Pharmacology and Immunology.

While working with Clinica Naturals, Dr. Mark aims to develop and endorse supplements that help the highest number of people using quality, science-backed ingredients as they do in Total Sleep Restore.

You can learn more about Dr. Mark at his Meno Clinic bio here. The Meno Clinic is a health and wellness clinic based in Jackson, Wyoming.

About Clinica Naturals

Clinica Naturals is a supplement company founded in Delaware in 2020. The company also lists an office in San Antonio, Texas.


You can contact Clinica Naturals via the following:

  • Mailing Address: 13423 Blanco Rd PMB 8024, San Antonio, TX 78216
  • Phone: 855-501-2207
  • Email: support@clinicanaturals.com

You can contact Clinica Naturals 24 hours a day, 7 days a week.

According to the official website, Clinica Naturals has “helped thousands of men and women” with various issues.

Final Word

Clinica Naturals is a health and wellness brand founded in 2020. The company’s flagship product, Total Sleep Restore, uses a blend of 7 natural ingredients to help you fall asleep and rejuvenate your body and mind while you sleep.

To learn more about the San Antonio-based health and wellness brand or to buy Total Sleep Restore online today, visit the official website at ClinicaNaturals.com.